Houston Texans vs. Indianapolis Colts Betting Odds, Analysis, NFL Pick

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Despite a rough start to the season, the Indianapolis Colts (6-6) can move ahead of the Houston Texans (6-6) in the race for the AFC South title with a victory in their second meeting Sunday. The Colts lost the first meeting 26-23 in overtime as three-point road underdogs after blowing a late 14-point lead, and they are listed as solid home favorites this time around.

Point spread: The Colts opened as 4.5-point favorites; the total was 46 early in the week, according to sportsbooks monitored by OddsShark (line updates and matchup report).

NFL pick, via OddsShark computer: 30.4-14.1 Colts (NFL picks on every game)

Why the Texans can cover the spread

Houston quarterback Brock Osweiler has not had a lot of great moments in his first season with the team since signing a four-year deal worth $72 million in the offseason.

But Osweiler’s best performance as a Texan came in the first meeting when he rallied his team back from a 23-9 deficit with two touchdown passes in the final 2:37 of regulation. Osweiler finished with 269 passing yards and outplayed Indy’s Andrew Luck, …

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