Cano’s 16th homer isn’t enough in San Diego

SAN DIEGO — Apparently eager to put a rough road trip behind them, the Padres wasted no time pouncing on Mariners spot starter James Paxton in their return to Petco Park on Wednesday night. They put six runs on the board in the first, kicked the extra point in the second and finished with a 14-6 victory over their Pacific Northwest foes.

Alexei Ramirez led the way with a pair of homers — his first two as a Padre at Petco Park — and a career-high five RBIs. Wil Myers, who finished a triple shy of the cycle, and Adam Rosales also went deep. The 19 hits for the Padres matched a season high, and the 14 runs were the most they’ve scored in a home game this season.

Robinson Cano took Padres starter Christian Friedrich deep in the top of the first inning, giving the Mariners a three-run lead before an out was recorded. But Friedrich settled in …

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