10 biggest spreads of the 2016 NFL season

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11:11 AM ET

CG Technology released lines for every NFL game in Weeks 1-16 this week. Below, we’ll run through the 10 games with the biggest spreads of the season.

Week 3: San Francisco 49ers at Seattle Seahawks (-14)

This marks the largest opening spread of the season, and one of four games in which Seattle is favored by double-digits. The 49ers, along with the Cleveland Browns, are one of two teams that aren’t favored in a game this season (San Francisco is a pick-em in three games). Last season, when these teams met in Seattle, the Seahawks won by 13 as a 14-point favorite, their fourth straight double-digit home win over San Francisco.

Editor’s PicksBrowns are underdogs in every game of 2016 season

Cantor Technology has issued lines for every game of the NFL season, apart from Week 17, and it doesn’t look good for Cleveland fans.

Week 2: San Francisco 49ers at Carolina Panthers (-11.5)

The week before going to Seattle, the 49ers play on the opposite coast as 11.5-point underdogs at Carolina. Just like the Seahawks, this is one of four games that the Panthers are a double-digit favorite in. Last season, the Panthers were the only team that went undefeated at home, outscoring their opponents by 16 PPG in Carolina.

Week 7: Cleveland Browns at Cincinnati Bengals (-11.5)

This is the only game that an AFC team opened as a double-digit favorite. The Browns — who are the biggest longshot to win the Super Bowl at …

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