Week 4 NFL Picks: Odds, Prop Bets and Predictions for Sunday’s Schedule

We’ve reached the fourth Sunday of the 2016 season, which means another day full of surprises, action and perhaps a little gaming are upon us.

If you’re the wagering type, you’ve probably had your fair share of roller coaster rides so far this season. There have been several surprises, along with enough injuries and wacky calls to muddle up even the clearest of pictures.

Sunday looks set to bring more of the same, as there are a number of intriguing matchups, beginning with the Indianapolis Colts and the Jacksonville Jaguars in London (at 9:30 a.m. ET, no less). We’re going to examine some of the more interesting wagering options and prop bets Vegas has to offer in Week 4.

First, though, let’s take a look at the latest odds, relayed by Odds Shark.

Safest Bets

Denver Broncos (-3) at Tampa Bay Buccaneers

The Denver Broncos travel to Florida in Week 4 to take on the Tampa Bay Buccaneers. Though the Broncos are undefeated and playing extremely well, it’s impossible to count the Buccaneers out because of the talent the team has on offense.

Buccaneers quarterback Jameis Winston has the offense rolling, in terms of yardage anyway. Tampa is ranked sixth in passing yardage (297 yards per game) and ninth in total yardage (383 yards per game).

The Buccaneers put up 32 points against a stout Los Angeles Rams defense in Week 3. Producing points against Denver shouldn’t be a major problem, even if the Broncos defense is a cut above that the Rams can boast.

The reason to go with Denver here, though, is its offense. Second-year quarterback Trevor Siemian has settled into the starting role nicely, and as a result, the Broncos offense is humming along.

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While Denver is only ranked 20th in total yardage (354 yards per game), the team is efficient when it comes to scoring. The Broncos are averaging 28 points per game, the fourth-best total in the NFL.

The challenge in Week 4 is a Buccaneers defense that Pro Football Focus rates just 26th overall. That defense surrendered 37 points to a Rams offense that had previously been woefully inept in 2016. It doesn’t seem likely to offer significant resistance against Siemian and Co.

Siemian, it would seem, presents a much bigger challenge than Rams …

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