NFL Predictions Week 3: Top Odds Picks, Projections for Every Game on Schedule

Does the NFL’s Week 3 slate seem like a collection of toss-ups or what?

There are some large point spreads for the Week 3 matchups, but you shouldn’t take them with much confidence.

For instance, after they fell to the Los Angeles Rams 9-3, are we sure the Seattle Seahawks are going to defeat the San Francisco 49ers by nearly two scores?

And sure, the Minnesota Vikings have no Teddy Bridgewater and will be without Adrian Peterson (knee) for at least four weeks, as Yahoo Sports’ Charles Robinson reported:

Been told meniscus options Adrian Peterson & #Vikings are weighing: partial repair & minimum 4 wk layup, or full repair w/ min 4 month layup

— Charles Robinson (@CharlesRobinson) September 19, 2016

But after what quarterback Sam Bradford did against the Green Bay Packers on Sunday, who knows? Perhaps the Vikings can remain within six points of the Carolina Panthers.

There are no sure things in the NFL, which is partly why we tune in week after week. Let’s take a look at the Week 3 lineup’s point spreads and make some picks:

What to Make of These Odds?

The Safe Bet: Arizona (-5.5) 

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