NFL Predictions Week 2: Upset Picks and Projections

The opening week of the 2016 NFL season provided bettors with plenty of upset material.

With the New England Patriots taking down the Arizona Cardinals, the Detroit Lions beating the Indianapolis Colts and the San Francisco 49ers blowing away the Los Angeles Rams, bettors received reinforcement in the idea that upsets can be a lucrative business.

Week 2 won’t prove much different, not with some interesting midweek lines still available. Bettors who like to complement the safe, bankroll-building bets with riskier upset plays for bigger gains have plenty of options thanks to some intriguing conference and divisional matchups.

Here’s a look at the entire slate, plus a few upsets to know.

NFL Week 2 Odds

Odds courtesy of Odds Shark.

Upsets to Pick Kansas City at Houston (-1.5)

A photo posted by Kansas City Chiefs (@chiefs) on Sep 11, 2016 at 5:16pm PDT

Here is an easy one for starters.

The Kansas City Chiefs took care of business against the Houston Texans to start the season last year and then whipped the team in the playoffs 30-0. Expect more of the same in Week 2 this year, especially after both teams trotted out notable performances in Week 1.

Last week, the Chiefs stormed out of a 17-point deficit to beat the San Diego Chargers, a divisional rival with upset on the mind. Alex Smith was electric, throwing for 363 yards and two scores. Spencer Ware filled in well for Jamaal Charles, rushing 11 times for 70 yards and a score and also leading the team in receiving with seven catches for 129 yards.

The Chiefs summed up his impact well:

“He lit a fire under us – got us going.” @spenceware11 sparks the Chiefs ➡️ https://t.co/LLziwRu5sL pic.twitter.com/dee1JJRUI1

— Kansas City Chiefs (@Chiefs) September 12, 2016

While it seems like the Chiefs had a tough time against a lesser opponent, the Texans didn’t look much better. Playing the Chicago Bears, who are looking a rebuild right in the eye, Houston got 231 yards and two scores from new quarterback Brock Osweiler but could never really put away the opposition, needing a 10-point fourth quarter to squeak out the win.

Now missing linebacker Brian Cushing thanks to injury, Houston will have a …

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